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Black Dog Venture Partners Acquires a 50% Stake in Restaurant Ordering Application, OnPlate Technologies

Scott Kelly to assume role of CEO. Company to relocate to Arizona.

Black Dog Venture Partners announced that it has acquired a 50% stake in Canadian based, OnPlate Technologies. OnPlate is a one-of-a-kind concierge, waiter, menu and payment processor, all wrapped into one easy-to-use app. Black Dog Founder, Scott Kelly will assume the role of CEO and the company plans to move its headquarters and begin its US launch in Arizona.

Scott Kelly commented on the acquisition “OnPlate’s founders, Frederic Sebag and Emmanuel Abikhzer have built great technology that allows customers to order quickly from their table, avoid wait times & enjoy better experiences, all with the ease of their smartphone. This completely contactless experience allows a safe and efficient means for restaurants to thrive during the pandemic and beyond. After a successful beta in Canada, we are excited to begin our US expansion in Phoenix”

“We are very excited to be working with Scott and the entire team at Black Dog Venture Partners. We truly believe our clients will benefit from this partnership as our models align beautifully with a focus on providing business owners with access, through the use of technology, to people and tools to help them improve in a variety of areas” added Emmanuel and Frederic, VP & Director of Operations, OnPlate.

Learn more and sign up today at OnPlate.App (https://www.onplate.app).

Follow OnPlate at:

Facebook – https://www.facebook.com/OnplateApp
Twitter – https://twitter.com/OnplateApp
Instagram – https://www.instagram.com/onplate_app/

About Black Dog Partners:
Black Dog Venture Partners is a business accelerator that provides venture capital consulting, corporate finance, business development, digital marketing and publicity for regional and national brands and fast-growing companies. Black Dog’s portfolio includes holdings in gaming, esports, entertainment, cybersecurity, and technology. Learn more at http://BlackDogVenturePartners.com

Press & Media Contact:
Scott Kelly
Black Dog Venture Partners
9920 South Rural Road, Ste. 108,
Tempe, AZ 85284
United States
+1 480-206-3435
scott@blackdogventurepartners.com
http://blackdogventurepartners.com

Readymade apps – Changing the entire landscape

Telco Tech, a renowned web application development company, has been offering readymade apps for various industries including food, grocery, laundry, etc.

Telco Tech is a technology partner that helps start-ups as well as businesses in a short span to start their business. They are far more than a readymade app solution company and their products are elegant proof of that. They provide fully customizable design and features according to modern business needs with market-ready advanced app.

The aim of the company is to help entrepreneurs do what they are best at, running the company. And they take care of all the technical aspects. Their ready-to-use, excellent app solutions and products are proving their own worth by making your business grow and redefine your place in the industry.

Some of the renowned Readymade Apps are –

Online Food Ordering System – It is a completely customized online food ordering system for your restaurant. It helps to take any food ordering business online with a mobile app and website.

TelcoGrocery – It is perfect grocery software, allowing your customer to order with your grocery store.

TelcoPizza – The company offers the complete software with inbuilt multiple features especially meant for pizza lovers.

Telco eCommerce – This software is suitable for any type of business such as food, clothes, grocery, cakes, etc.

Laundry ordering system – It is the best solution to manage any laundry business online.

Telco Taxi – Businesses can automate and modernize their taxi business with Telco Taxi Solution.

They also offer professional web design services at affordable rates to help businesses attract more visitors and keep them on your site! They always strive to make long lasting relationships with their clients.

For more information about readymade apps for android, On-demand Delivery App, readymade apps solutions in Poland, readymade software, readymade apps or readymade Mobile App Solutions and mobile app development, please visit – https://telcotech.pl/

Telco Tech is a best web application development company, which offers outstanding solutions. They provide top-notch web and mobile app development services through the use and enhancement of the latest out there technologies. They have a handpicked selection of the finest developers of web & mobile apps, who always believe that any task can be done more intelligently and any existing system can be challenged, and ultimately improved.

MBAF’s Marta Alfonso Elected Vice Chair of New York State Society of CPAs Committee

National public accounting and advisory firm MBAF is proud to announce that Marta Alfonso, principal in the Management Advisory Services Department and the principal-in-charge of the Litigation Support Division, has been appointed vice chair of the Bankruptcy and Financial Reorganizations Committee of the New York State Society of CPAs (NYSSCPA).

The NYSSCPA aims to educate, connect, and grow their membership within the CPA industry. Alfonso will be working alongside Edward L. Arcara, the president-elect of the NYSSCPA, in fulfilling goals of future partnerships with business groups, chambers of commerce and other professional organizations. Additionally, she will be recognizing and responding to the needs of the members of the Society in specialized areas such as bankruptcy, reconstructing, and consulting.

As a principal in the Management Advisory Services Department and principal-in-charge of the Litigation Support Division at MBAF, Alfonso has an extensive background in litigation consulting, forensic accounting, insolvency, and bankruptcy. In addition, she leads MBAF’s Distressed Business Advisory Team. With a strong background in litigation consulting, forensic accounting, insolvency and bankruptcy, turnarounds, and financial management, Alfonso offers extensive financial experience and a deep understanding of critical financial litigation issues. Trained as both an accountant and an attorney, she has worked in a range of consulting and in-house corporate roles since 1983.

For more information on MBAF, visit our website at www.mbafcpa.com.

About MBAF

Now in its 50th year of operation, MBAF is ranked nationally as a Top 40 accounting and advisory firm by Accounting Today and has been named one of the Best of the Best firms in the country by INSIDE Public Accounting for the past 18 years consecutively, being chosen for demonstrating long-term consistency and exceptional performance, regardless of outside factors. Named a 2020, 2019, 2018, and 2017 South Florida Business Journal Best Places to Work finalist and a 2018 and 2017 Accounting Today Best Accounting Firm to Work For, MBAF is committed to creating an engaging and supportive workplace for its more than 650 highly qualified principals and employees. The MBAF team serves domestic and international clients across a broad range of industries and practices in more than 55 countries and all 50 states. Its offices are located in New York, Valhalla (Westchester, NY), Miami, Coral Gables, Naples, Las Vegas, Baltimore, Boca Raton, Boulder, Fort Lauderdale, Palm Beach, Orlando, and India.

MBAF – CPAs and Advisors
1450 Brickell Avenue, 18th Floor, Miami, FL 33131
Tel: 305-373-5500
Fax: 305-373-0056
URL: https://www.mbafcpa.com/
Email: mbaf@mbafcpa.com

TARGETING 6X GROWTH,DOCONLINE APPOINTS TANUJ SAXENA AS CHIEF DISTRIBUTION OFFICER

Bengaluru: September ,2020: DocOnline Health, a digital primary healthcare company, announces the appointment of Tanuj Saxena as its Chief Distribution Officer with immediate effect.

Tanuj is a healthcare and insurance industry veteran and was previously Senior VP Business Developmentfor vHealth by Aetna. His previous stints also include Aegon Life Insurance, Max Bupa Health Insurance and Royal Sundaram General Insurance.

In his new role, Tanuj will be responsible for leading the distribution strategy for DocOnline India and accelerateDocOnline’s growth in the dynamic and evolving digital healthcare ecosystem in India.

Manasije Mishra, the Managing Director of DocOnline India, said “We are delighted to get Tanuj on board. In a country that is looking to build a robust, equitable and accessible healthcare system with new and sustainable policies, Tanuj’s industry expertise, strong relationship within BFSI sector and his customer-centric approach will help us create partnership opportunities& leveragethe strengths of our distribution partners.”

Tanuj Saxena commented “Telemedicine and digital primary care services are playing a crucial role in solving our country’s healthcare challenges. I am privileged to work for an organization that is at the forefront of changing how Indians access healthcare. The COVID 19 pandemic has taught us many lessons, most important of which is the role that technology can play in addressing unmet healthcare needs of Indians.”

DocOnline India works with the Government, NGOs, companies and consumers to enable a Healthier India. DocOnline is currently serving over 500,000 people in India. Over the last six months DocOnline has added 300,000 new customers,five new distribution partnerships with India’s leading NBFCs & Insurance companies and over 100 new corporate relationships. DocOnline is on an upward trajectory of growth. Recently, DocOnline also received recognition from CEO Insights Magazine as one of the Top 10 mHealth Service Providers for 2020 in India.

About DocOnline

DocOnline Group (DocOnline Health India Private Limited and DocOnline Consulting Private Limited) is a digital healthcare company providing online doctor consultation, EMR and e-clinic solutions through its proprietary platform.With their healthcare partners, DocOnline facilitates doorstep delivery of blood check-ups, medicine delivery, and home care treatment. The remote consultations are delivered via telephone, video, and chat, and the prescriptions are sent via email and SMS.They harness innovative technology-based solutions to provide quality health care services through their in-house team of doctors. Their motto is to provide quality primary healthcare to anyone, anywhere. They have offices in Bengaluru, Mumbai, Gorakhpur and New Delhi.

Singapore Scientists Discover Human Liver Cancer Cells Masquerading As Fetal-Like Cells

A team of researchers and clinician-scientists from A*STAR’s Genome Institute of Singapore (GIS), Singapore Immunology Network (SIgN), National Cancer Centre Singapore (NCCS), and KK Women’s and Children’s Hospital (KKH), have identified a pivotal “fetal-like” reprogramming of the tumour ecosystem in human hepatocellular carcinoma (HCC). This study leveraged the platform established by the National Medical Research Council (NMRC) Translational and Clinical Research (TCR) Flagship Programme in Liver Cancer and was recently published in Cell on 24 September 2020.

HCC, or primary liver cancer, is the sixth most common cancer in the world, and the second most common cause of cancer deaths globally. It is estimated that approximately 80% of all HCC are found in Asia. Tumours represent a complex ecosystem of diverse cell types that exhibit molecular and functional heterogeneity and plasticity. Previous studies have noted the similarities between embryonic development and tumours, specifically in the expression of fetal-like antigens in cancers. Most notably, alpha-fetoprotein (AFP) is one of the key onco-fetal proteins found to be elevated in more than 80% of HCC, especially in those with poorly differentiated cell types which are clinically more aggressive. The fetal immune system and placental-fetal system are known to be largely immunologically tolerant, allowing their co-existence within the mother until birth. It has long been suggested that cancers may have similar mechanisms to avoid rejection by the body. While it is known that HCC can undergo onco-fetal reprogramming, the relationship between HCC and its micro-environment has not been examined in detail.

In this comparative study, the researchers mapped approximately 200,000 single cells in the human liver across the timeline from fetal development to terminal liver cancer. It led to the discovery of two new fetal-associated cell types in the tumour ecosystem in HCC. Specifically, the team identified the reappearance of fetal-like endothelial cells that are responsible for blood supply, and fetal-like macrophages, an immune cell type that serves as the body’s first line of defence against pathogens, but are also associated with tissue homeostasis.

The researchers discovered that during development of the fetal liver (a process that shares many characteristics typically associated with cancer growth), these cell types (fetal endothelial and macrophages) help in organ growth and protect the tissue against the body’s own immune system. The team identified the sequential activation of VEGF and Notch signalling pathways that led to fetal-like reprogramming of endothelial cells and macrophages. Importantly, the authors showed that these signalling pathways are activated during fetal-liver growth, and switched off thereafter, but are re-activated during the development of liver cancer.

A dividing cancer cell first activates VEGF pathway in endothelial cells, which in turn communicate with macrophages in tumours via Notch-Delta interactions. The fetal-like programme in tumours allows uncontrolled growth and protection from the immune system. This study provides unprecedented and fundamental insights into the processes that drive cancer development, and may provide new therapeutic strategies to re-activate the immune system in the fight against cancer.

Dr Ramanuj DasGupta, cancer biologist and Senior Group Leader at GIS, and the lead corresponding author of the study, said, “Our research underscores a fundamental understanding of how early developmental processes can be hijacked by cancers in order to facilitate their own growth, and escape immune surveillance. This study also opens up exciting possibilities for the discovery of biomarkers and novel therapeutic targets associated with non-malignant cells, especially in the context of combinatorial immunotherapy with anti-angiogenic drugs. Most importantly, it highlights the power of like-minded scientists and clinicians coming together to solve big problems. I am absolutely thrilled to be working with this dream-team of exceptional scientists and clinicians.”

Dr Ankur Sharma, Research Scientist at GIS, the first and co-corresponding author of the study, said, “Our research provides insights into the mirror worlds of fetal and tumour ecosystem, where certain cell types first appear during organ development and later reappear in cancer. The ‘reappearance’ of fetal-like cells provides the perfect environment for tumour growth by supressing the immune system. Our work demonstrates the importance of embryonic macrophages in tumour growth and immune suppression. This study opens new avenues to understand the embryonic origin of cancers and its implication in discovering new therapeutic approaches, especially in the realm of immunotherapy.”

Dr Florent Ginhoux, scientist and Senior Principal Investigator at SIgN, and co-corresponding author of the study said, “The macrophages are one of the first immune cells to arise during development as their raison d’être is to provide adequate organ building and tissue maintenance. These embryonic macrophages are endowed with immune-suppressive properties as inflammation too early would be detrimental to the correct development of fetal tissues. Our work uncovers that tumour cells exploit embryonic macrophage’s raison d’être for their own growth, by recreating an artificial fetal-like environment and taking macrophages ‘back in time’ mimicking early developmental settings. This study will help to understand the importance of macrophage ontogeny in cancer development and open new strategies to eradicate cancer.”

Prof Pierce Chow, Clinician-Scientist and Liver Surgeon at NCCS, Principal Investigator of the NMRC TCR Flagship Programme in Liver Cancer, and co-corresponding author of the study, said, “This study provides mechanistic confirmation of what many liver cancer specialists have suspected – regression to a fetal state allows HCC to grow aggressively. The findings potentially opens up new approaches in the prevention and treatment of HCC. It is also a showcase of what multi-disciplinary collaborative research between clinician-scientists from different specialities and scientists with different expertise can achieve.”

Prof Chow who is also a Programme Director with Duke-NUS Medical School added that he may include the investigation for proteins uncovered by this study in a prospective cohort study of patients at high risk of developing liver cancer, which has been planned to start at the end of 2020.

Prof Jerry Chan, Clinician-Scientist and Senior Consultant at KKH’s Department of Reproductive Medicine and co-author of the study, said, “Globally, cancer cases have risen rapidly over the years. Understanding the behaviour of how cancer cells reprogramme their environment to simulate a fetal environment, and thereby promoting their growth and avoiding immune destruction, may be key to developing a cure. KKH is proud to contribute to this novel discovery through underlying expertise in the developing fetal immune system, in collaboration with A*STAR and others.”

Prof William Hwang, Medical Director at NCCS, said, “Indeed, the multi-institutional collaboration has allowed the team to leverage on each other’s expertise, leading to the discovery of onco-fetal reprogramming in liver cancer. I’m glad we are one step closer to understanding and treating liver cancer.”

Prof Patrick Tan, Executive Director of GIS, said, “The discovery of onco-fetal reprogramming in liver tumours opens up new avenues of investigating this process in other cancers and inflammatory diseases. This work also demonstrates the power of single-cell and spatial genomics in uncovering fundamental biological insights. It is a true example of ‘SG United’ where scientists across the different Singapore institutions formed a team to discover new biological processes with translational implications in the clinic.”