Advanced ChemTech offers coupling reagents to help chemists synthesize potential drugs faster and more efficiently.
Coupling reagents are chemical agents used to facilitate the joining of two molecules to form a new bond. They are crucial in creating various organic compounds, including peptides and nucleotides. Advanced ChemTech proudly offers access to coupling reagents to empower drug discovery.
Chemists can efficiently create bonds between molecules, allowing them to synthesize a wide array of potential drugs with diverse structures and functions. Our coupling reagents enable the rapid assembly of complex molecules, significantly speeding up and optimizing pharmaceutical research.
By optimizing the synthesis process, researchers can accelerate their work, moving more quickly from concept to clinical trials. This outcome reduces development costs while allowing for faster access to new therapies.
TYPES OF COUPLING REAGENTS
Each coupling reagent has its own set of properties and applications. Popular options include carbodiimides, uronium or phosphonium salts, and aminium or guanidinium reagents.
Carbodiimides are among the most traditional coupling reagents used to form amide bonds. Uronium and phosphonium salts are more efficient and produce fewer side reactions, which makes them especially useful for high-purity peptide synthesis.
Aminium and guanidinium reagents enhance efficiencies, further reducing side reactions and improving yield.
Peptide coupling reagents for drug discovery from Advanced ChemTech enable the rapid assembly of complex molecules, significantly speeding up the discovery and optimization of new therapeutic agents. They are instrumental in peptide drug development, where the precise assembly of amino acids is critical for the activity and specificity of the drug.
BENEFITS OF ADVANCED CHEMTECH COUPLING REAGENTS
One of the challenges in synthesizing peptides and proteins is the potential for side reactions that can lead to impurities. Our coupling reagents are engineered to minimize them, ensuring a cleaner synthesis process.
Our reagents stand out for their crucial role in synthesizing peptides, proteins, and other compounds. Advanced ChemTech delivers multiple advantages with our cutting-edge approach.
The precision and efficiency offered by these reagents allow researchers to synthesize complex molecules with high purity, significantly reducing the time and resources needed for this stage of drug development.
Whether one works on small-scale laboratory experiments or scaling for commercial production, our coupling reagents provide adaptability across different synthesis scales. That makes them invaluable for research, development, and manufacturing throughout each development phase.
In return, our team contributes to improving drug properties such as stability, solubility, and bioavailability. By enabling the precise synthesis of molecules, these coupling reagents help tailor pharmaceutical properties to enhance their performance.
About Advanced ChemTech
Based in Louisville, Kentucky, Advanced ChemTech provides various fine chemicals to the research and pharmaceutical market. These chemicals vary massively, including amino acids, peptides, resins, reagents, and more. We are Leaders in instrumentation, and provide TETRAS™, a state-of-the-art synthesizer for peptide synthesis.
Advanced ChemTech has all the chemicals you need, whether for pharmaceutical research or the market, or perhaps a school science project, required re-stock for a commercial entity, or other requirements. Whatever you need, the Chemtech team is here to help you; you can even read their newly released blog for free information and advice. To find out more information about the team and their processes, you can also reach out via https://www.advancedchemtech.com/contact/
RIGS, a family-owned business in Ouray County, offers guided fly fishing trips to help people experience Colorado’s best fly fishing spots.
Colorado is America’s fly fishing paradise! For those who live here, finding the best rivers and streams for fly-fishing happiness is relatively simple. Coming from out-of-state is often a different story!
RIGS is a full-service fly shop and guide service from Ridgway, CO. For twenty-three years, they have been well-respected outfitters from southwest Colorado, providing guided fly fishing on the Uncompahgre, San Miguel, High Country Cimarron, Curecanti National recreation Area and lower Gunnison River/Gunnison Gorge Wilderness River sections. They pride themselves on being a family business with amazing staff that provide best-in-class guided fly fishing experiences for all. Their full service Fly Shop offers a curated selection of western Colorado’s finest fly goods from the industry’s leading manufactures.
Owners Tim and Heather Patterson say about a day on the river with RIGS, “It’s not just about the fishing, it’s about what you learn from the people you meet. Fishing is just the conduit. We want people to leave with the sentiment – I want to do that again!”
WHY CHOOSE COLORADO FLY FISHING?
Colorado offers more than 9,000 miles of streams to explore, with Ouray County having some of the best locations. Each location offers something unique and fun to try, whether one casts lines into the rapids or a quiet, tranquil location.
The state is committed to conservation and sustainable fishing practices. Colorado has made significant efforts to protect its natural waterways and the fish that inhabit them, ensuring that the ecosystems remain balanced.
There is also the challenge that fly fishing in Colorado represents. It requires a blend of patience and skill with an understanding of the local ecosystem. That’s where RIGS Fly Shop & Guide Service can help!
Our Colorado fishing report simplifies finding the best places to pursue trout and other species, while our guided tours, fly fishing guide school, and local knowledge provide an affordable way to maximize outdoor time.
TOP PLACES TO VISIT FOR FLY FISHING IN OURAY COUNTY
Located in the majestic San Juan Mountains, our paradise is a haven for those looking to cast their lines in some of the most tranquil and picturesque waters in the state.
Here are some of the best spots to visit when the urge to do some Colorado fly fishing strikes.
Ridgway State Park. Located a little north of Ouray, this beautiful location encompasses the Uncompahgre River and the local reservoir. It offers stillwater and river-based fly fishing opportunities.
Cimmaron River. This spot is known for offering rainbow and wild brown trout. The river is narrow and technical, which makes it an exciting challenge for experienced anglers.
Canyon Creek. Our guides can take visitors through the national forest to enjoy a more rustic experience. Native cutthroat trout are here, and the remote location means the odds of running into someone are minimal.
Dallas Creek. This area feeds into the reservoir while providing a more secluded fishing experience away from the popular spots.
Fly fishing in Ouray County is as much about the experience and the breathtaking scenery as it is about the catch. RIGS provides the knowledge needed to enjoy each moment out there in our fishing report.
About RIGS Fly Shop & Guide Service
Based in Ridgway, RIGS Fly Shop & Guide Service was founded in 2001 by Tim Patterson to help others embrace his unwavering love of fly fishing. Tim’s wife Heather is a fourth-generation Colorado native, and they have brought an incredible team together that share the same passion for outdoor adventures. Through partnerships with the US Forest Service, National Park Service, Bureau of Land Management, and Colorado State Parks & Wildlife, each guest can explore diverse waters and personal experiences.
In addition, nine other Intermountain hospitals in Utah were ranked among the nation’s best hospitals on this year’s top 100 hospitals list, according to PINC AI and Fortune.
Fortune magazine and PINC AI have ranked Intermountain Medical Center in Murray, Utah as the number one major teaching hospital in the nation for 2024.
Nine other Intermountain Health hospitals in Utah were also ranked among the nation’s best hospitals on this year’s top 100 hospitals list, according to PINC AI and Fortune, including:
Intermountain Alta View Hospital in Sandy
Intermountain American Fork Hospital
Intermountain Cedar City Hospital
Intermountain Layton Hospital
Intermountain Logan Regional Hospital
Intermountain Park City Hospital
Intermountain Riverton Hospital
Intermountain St. George Regional Hospital
Intermountain McKay-Dee Hospital was listed forth for teaching hospitals while Intermountain St. George Regional Hospital placed second in the category for Large Community Hospitals.
“When 10 percent of all the hospitals on a prestigious list like Fortune are from Intermountain Health, it shows how the innovative, caring and compassionate work our caregivers do on a daily basis is helping fulfill our vision of being a model health system – a charge given when our system was formed in 1975,” said Rob Allen, president and CEO of Intermountain Health. “I’m proud of our caregivers for the work they do and the impact it has on our communities. Their work is an inspiration to me and to others.”
The Fortune rankings analyzed publicly available data from more than 2,600 hospitals across the nation to determine top performers in clinical outcomes, patient experience, operational efficiency, and financial health.
“Our caregivers are at the forefront of innovation in healthcare and Intermountain Medical Center being ranked the top teaching hospital in the country shows that our vision is working,” said Ralph Jean-Mary, CEO of Intermountain Medical Center in Murray.
The annual Fortune and PINC AI Top 100 list is broken down into multiple categories with 40 being for teaching hospitals, and the remaining 60 slots for community hospitals.
To see the full Fortune Top Hospitals List for 2024, click here.
About Intermountain Health
Headquartered in Utah with locations in seven states and additional operations across the western U.S., Intermountain Health is a nonprofit system of 33 hospitals, 385 clinics, medical groups with some 3,900 employed physicians and advanced care providers, a health plans division called Select Health with more than one million members, and other health services. Helping people live the healthiest lives possible, Intermountain is committed to improving community health and is widely recognized as a leader in transforming healthcare by using evidence-based best practices to consistently deliver high-quality outcomes at sustainable costs. For more information or updates, see https://intermountainhealthcare.org/news.
In a significant move to bolster brain health and cognitive performance, Algine Plus is thrilled to announce the availability of its groundbreaking supplement, Algine Plus Phosphatidylserine, on One Lavi, the esteemed online retailer for health, beauty, and wellness products. This innovative supplement is expertly crafted to decelerate brain aging, mitigate stress, and elevate mental functions, marking a pivotal advancement in dietary supplements dedicated to enhancing cognitive well-being.
Phosphatidylserine, the star ingredient in Algine Plus Phosphatidylserine, is backed by rigorous scientific studies showcasing its profound impact on brain health. These studies underscore the supplement’s efficacy in supporting crucial cognitive functions, including memory, processing speed, and focus, making it an indispensable addition to the health regimen of those seeking to maintain sharp mental acuity throughout their lives.
Each bottle of Algine Plus Phosphatidylserine contains 30 premium capsules, meticulously formulated to deliver the optimal concentration of phosphatidylserine. This ensures that individuals receive the precise dosage needed to reap the maximum benefits for their brain health and overall mental performance.
Algine Plus, a pioneer in algae-based dietary supplements, brings over 35 years of industry expertise to the development of its products. Founded by Rolf Nilsson, a world champion in military pentathlon, Algine Plus harnesses the purity and power of natural resources sourced from Greenland and Iceland. The company’s unwavering commitment to quality, innovation, and customer satisfaction is reflected in its comprehensive range of supplements designed to support optimal health and well-being.
One Lavi stands as a beacon of trust and excellence in the online retail space, offering a curated selection of health, beauty, and wellness products. The inclusion of Algine Plus Phosphatidylserine in One Lavi’s product lineup underscores a shared commitment to providing customers with access to high-quality supplements that enhance life quality and promote holistic health.
To explore the benefits of Algine Plus Phosphatidylserine and make a purchase, please visit OneLavi.com/AlginePlusPhosphatidylserine.
Disclaimer: The statements made regarding these products have not been evaluated by the Food and Drug Administration. This press release is not a substitute for professional medical advice, diagnosis, or treatment. The news site hosting this press release is not associated with Algine Plus. It is merely publishing a press release announcement submitted by a company, without any stated or implied endorsement of the product or service.
About Algine Plus
Algine Plus is a leading provider of algae-based dietary supplements with over 35 years of experience in the industry. Developed by Rolf Nilsson, a world champion in military pentathlon, Algine Plus offers a range of high-quality, natural products sourced from Greenland and Iceland. Their comprehensive supplements are designed to support optimal health and well-being, catering to a wide range of customer needs. Algine Plus is committed to delivering excellence through innovative formulas, certified production processes, and a focus on customer satisfaction.
The entire Bombardier team is proud to celebrate Moodys rating upgrade announced yesterday. This most recent upgrade places Bombardier at a B1 rating with a stable outlook and reflects the companys consistent performance to date throughout its turnaround. As we outlined in our2024 Investor Daythis week, we have a strong foundation upon which to keep improving key balance sheet metrics.
Bombardier continues to build its resilience through growth pathways that thoughtfully diversify revenue streams all while creating additional margin and cash upside. Dynamic businesses like Services and Bombardier Defense not only add value to our company, but they do so by offering our customers unique and flexible solutions.
We have created a lot of momentum, that is well embodied in the launch of our new forward-looking brand identity. Over the past years, Bombardier team members across our various businesses have executed to plan to near perfection, intently focused on what we control. This approach continues to raise us to higher altitudes of performance on debt reduction, earnings and positive free cash flow generation.
About Bombardier
At Bombardier (BBD-B.TO), we design, build, modify and maintain the worlds best-performing aircraft for the worlds most discerning people and businesses, governments and militaries. That means not simply exceeding standards, but understanding customers well enough to anticipate their unspoken needs.
For them, we are committed to pioneering the future of aviationinnovating to make flying more reliable, efficient and sustainable. And we are passionate about delivering unrivaled craftsmanship and care, giving our customers greater confidence and the elevated experience they deserve and expect. Because people who shape the world will always need the most productive and responsible ways to move through it.
Bombardier customers operate a fleet of approximately 5,000 aircraft, supported by a vast network of Bombardier team members worldwide and 10 service facilities across six countries. Bombardiers performance-leading jets are proudly manufactured in aerostructure, assembly and completion facilities in Canada, the United States and Mexico.
For Information
For corporate news and information, including Bombardiers Environmental, Social and Governance report, as well as the companys plans to cover all its flight operations with a Sustainable Aviation Fuel (SAF) blend utilizing the Book and Claim system visit bombardier.com.
Magna International Inc. (TSX: MG; NYSE: MGA)reported financial results for the first quarter ended March 31, 2024.
Our first quarter results exceeded our expectations for sales and earnings, excluding the impact of impairment charges. As a result of our continued focus on cost containment, customer recoveries and operational excellence, we are maintaining our Adjusted EBIT margin outlook range for 2024 and see continued progress on our planned margin expansion despite uncertainty of electrification volumes and product mix in the industry.
Leaders of the nations legacy civil rights organizations came together to endorse theFreedom to Learncampaign and join Professor Kimberl Crenshaw, Co-Founder and President of the African American Policy Forum in rejecting the effort to suppress Black history and our nations history, roll back more than half a century of hard-won civil rights victories, and undermine the ultimate ideal of this country — to achieve an inclusive democracy for all.
Freedom to Learn is a movement initiated by a coalition of civil rights, human rights, and other social and racial justice organizations to fight the far-right campaign to suppress truthful history, marginalize Black and LGBTQ+ teachers and students, and to repeal decades of anti-racist, pro-equality policies. As we commemorate the 70th anniversary ofBrown v. Board of Educationand the 60th Anniversary of Freedom Summer we face a frightening reality. Progress toward more racially integrated and inclusive schools that can serve as nurseries of our democracy is under grave threat by those who fear the changing demographics of American society, and thwart the political power of people of color and other marginalized communities.
Book bans that target Black and LGBTQ+ authors and efforts to sanitize and suppress curriculum are tools of a larger effort to erase the history of segregation and white supremacy with the intent of re-configuring our democratic institutionsin a way that undermines equity.. The extremist has outlined this very strategy in its manifesto, otherwise known as Project 2025 a detailed, nearly 900-page master plan that seeks to federalize the worst of red-state legislation to shut down public education, civil rights, and our democracy. This draconian anti-democratic agenda seeks to roll back federal protections for civil rights and to further erode our democratic norms.
As civil rights leaders representing legacy organizations originally formed to achieve the ideals of this nation – A More Perfect Union – we are standing together to push back on the extremely troubling and explosive attacks on any effort to create an inclusive democracy by attacking not only Black history, but any DEI efforts. The threats ahead are potentially devastating as this well-funded right-wing minority seeks to foreclose the possibility of an equitable future through anti-democracy initiatives like Project 2025. We know that the far right is attacking the freedom to learn because they know that knowledge is power.
That is why the Freedom to Learn campaign is vital. Together we stand against the fearmongers and would-be autocrats who falsely allege that anti-racist teachings are a form of racism. We are the majority who stand for the honest reckoning with our history that is necessary to create an inclusive, multi-racial democracy. May 3rd is the second annual Freedom to Learn National Day of Action, which also kicks off Freedom Summer 2024. Throughout the summer were building our collective counter power to defend our democracy.
On the 60th anniversary of Freedom Summer 1964, we stand together to honor this legacy by fighting for our freedom. Just as activists descended upon Mississippi to establish freedom schools and for the right to vote we will join together to protect these rights against contemporary efforts to turn us back. Across the nation standing firm against the U-Turn on civil rights. We arent going back.
Marc H. Morial, President and CEO, National Urban League
Rev. Al Sharpton, Founder and President, National Action Network
Melanie Campbell, President and CEO, National Coalition on Black Civic Participation and Convener of the Black Womens Roundtable
Derrick Johnson, President and CEO, NAACP
Damon Hewitt, President and Executive Director, Lawyers Committee for Civil Rights Under Law
Maya Wiley, President and CEO, The Leadership Conference on Civil and Human Rights
Shavon Arline-Bradley, President and CEO, National Council of Negro Women
). Based in Silicon Valley, Lex Machina is part of LexisNexis, a leading global provider of legal, regulatory, and business information and analytics. For more information, please visitwww.lexmachina.com.
Anticipates Not Less Than 120% Rise in Consolidated Profit Attributable to Shareholders
HONG KONG, May 5, 2024 – (ACN Newswire) – JBM (Healthcare) Limited (“JBM Healthcare” or the “Company”; Stock Code: 2161, together with its subsidiaries, the “Group”), a leading branded healthcare products marketer and distributor in Hong Kong, has announced a positive profit alert. Based on a preliminary review of the unaudited consolidated management accounts of the Group for the financial year ended 31 March 2024 and the information currently available to the board of directors of the Company, the Group is expected to record an increase in the consolidated profit attributable to shareholders for the year ended 31 March 2024 (“Consolidated Profit”) by not less than 120% as compared to that for the same period last year.
The significant increase in Consolidated Profit stems from a combined effect of the improvement in overall retail market sentiment due to the gradual recovery of tourist travel to Hong Kong, alongside the effective execution of advertising and marketing strategies for our key brands under the proprietary medicine category, notably Po Chai Pills and Ho Chai Kung. This promising performance underscores our disciplined execution of growth strategies along the offline and online platforms, with positive progress being made on the cross-border e-commerce trade.
JBM Healthcare has a diversified portfolio spanning branded medicines, proprietary Chinese medicines, and health and wellness products. The Group continues to make progress on its strategic priorities, including expanding e-commerce platforms locally and cross-border, exploring opportunities in traditional Chinese medicines for Hong Kong and the Greater Bay Area, adapting its product mix to consumer trends, and enhancing commercial execution.
For details, please refer to the announcement on HKEX.
About JBM (Healthcare) Limited (Stock Code: 2161)
JBM Healthcare is a Hong Kong-based company that markets and distributes branded healthcare products across Greater China, Southeast Asia, and certain other countries. The Group is a unique field player with marketing expertise and a drug heritage that prioritises product efficacy and quality to meet consumers’ healthcare needs. As a renowned healthcare brand operator in Hong Kong, the Group carries a wide-ranging portfolio of branded healthcare products comprising branded medicines, proprietary Chinese medicines, and health and wellness products, which include well-recognised household brands such as Po Chai Pills, Ho Chai Kung Tji Thung San, Contractubex, BITE-X, Mederma for Kids, Tong Tai Chung Woodlok Oil, Flying Eagle Woodlok Oil, Saplingtan, Shiling Oil and Konsodona Medicated Oil. JBM Healthcare has been a constituent stock of the MSCI Hong Kong Micro Cap Index since 27 May 2021. For more details about JBM Healthcare, please visit: www.jbmhealthcare.com.hk
The Sons and Daughters of the Vietnam War proudly announces the installation of Dennis Schlemmer as its National President, effective May 2, 2024. Hailing from Taylor, Michigan, Schlemmer assumes the prestigious role as the second national president of the esteemed organization.
Schlemmer’s connection to the Vietnam War runs deep; he joined the organization through the war service of his father, Dennis C. Schlemmer, who served with the U.S. Army 864th Engineer Battalion from 1968-1970. This personal connection fuels his passion for honoring the sacrifices made by those who served during this tumultuous period in history.
Founded in 2021 as a special project through the National Vietnam War Museum in Weatherford, Texas, the Sons and Daughters of the Vietnam War has rapidly grown to become a vital institution dedicated to honoring the legacies of those who served in the Vietnam War. The organization’s mission encompasses historical, patriotic, and non-political initiatives, with a focus on fostering community, providing support, and advocating for its members.
Outgoing president Katee Girling of St. Paul, MN will transition to the position of National Junior Past President, bringing her valuable leadership and experience to continue guiding the organization’s vision.
In his new role, Schlemmer will spearhead the organization’s efforts to maintain and uphold memorials honoring the Vietnam War, as well as to educate and inform individuals seeking insight into this pivotal period of history. Additionally, he will collaborate closely with The National Vietnam War Museum to promote understanding and appreciation of the Vietnam War for generations to come.
“It is an immense honor to step into the role of National President of the Sons and Daughters of the Vietnam War,” said Dennis Schlemmer. “I am deeply committed to advancing our mission of honoring those who served and creating a supportive community for all members. Together, we will continue to uphold the legacy of the Vietnam War and ensure that its significance is never forgotten.”
Dennis Schlemmer brings a wealth of experience and dedication to his new position, alongside his professional role as an Operations Support Manager for Little Caesars International, based out of Detroit, Michigan.
For more information about the Sons and Daughters of the Vietnam War and its initiatives, please visit www.sdvw.org.
Sons and Daughters of the Vietnam War Dennis Schlemmer 313-409-5496 www.sdvw.org
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