From optimizing particle size to choosing the right nanocarrier systems, Oligonucleotide Therapeutics and Delivery conference will address delivery to non-hepatocyte cells such as cancerous tissues and overview the most successful platforms.
Download a copy of your brochure to find out who will be speaking at the upcoming conference in September www.oligonucleotide.co.uk/PRCOMpr4
Clinical Advances of RNAi Therapy
Treating diseases with antibody oligonucleotide conjugates: Combining the selectivity of antibodies with the specificity of oligonucleotide drugs
– Antibody oligonucleotide conjugates utilize the selectivity of antibody delivery and the specificity of oligonucleotide therapeutics to treat diseases
– AOC1001 is designed to treat myotonic dystrophy type 1
– Other AOCs are in development to address muscle disease and other disorders
Arthur A Levin, Chief Scientific Officer, Avidity Biosciences Inc
Delivery of Novel siRNA constructs for treating cancer
– Creating siRNA payloads for cancer treatment
– Understanding the challenges of cell-specific delivery: how to get size and efficacy right?
– Choosing the appropriate delivery system
– Presenting success and future steps
David Evans, Chief Scientific Officer, Sirnaomics, Inc
Recent clinical progress with RNAi loaded KRAS-LODER for pancreatic tumour
– Introducing the RNAi loaded KRAS-LODER for targeting KRAS mutations
– Overviewing recent clinical success in phase II trials
– Presenting phase II clinical trials results including primary and secondary endpoints
– Outlining next steps of programme
Amotz Shemi, CEO, Silenseed
INT-1B3 (miR-193a-3p mimic): from bench-to-bedside
– Focus on microRNA R&D
– Success (bench-to-bedside) story for Oncology therapeutic intervention
– Preclinical to first in human study transition
Michel Janicot, CDO, InteRNA Technologies BV
Register online: www.oligonucleotide.co.uk/PRCOMpr4
Early bird offer register by 30th June and save £100
Proudly Sponsored by ChemGenes | Genscript | Tosoh Bioscience
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