Mitsubishi Heavy Industries, Ltd. (MHI) made significant technological contributions to the first imagery acquisition conducted by the X-ray Imaging and Spectroscopy Mission (XRISM) Satellite announced by the Japan Aerospace Exploration Agency (JAXA) on January 5 (Note1). MHI technology supported the data acquisition of the distribution and chemical composition of high-temperature plasma weaving through the galaxies by the XRISM satellite’s onboard soft X-ray imager (Xtend) and soft X-ray spectrometer (Resolve). XRISM has been developed by JAXA.
XRISM’s mission is to document, in unprecedented detail, the formation of stars, galaxies and galaxy clusters. MHI, which serves as manufacturer of the mission instruments, is responsible for designing and manufacturing Xtend’s X-ray charge coupled devices (CCD) (Note2) detector and the data processors for Xtend and Resolve. XRISM, together with JAXA’s “Smart Lander for Investigating Moon” (SLIM), was launched from the Tanegashima Space Center in Kagoshima Prefecture on MHI’s H-IIA Launch Vehicle No. 47 (H-IIA F47) on September 7, 2023 (Note3).
Thanks to high-precision placement and assembly of the detector’s four CCDs, Xtend’s X-ray CCD camera array captured a wide viewing coverage in just a single observation. Previously, this would have required multiple X-ray observations. The mission data processors employed on both Xtend and Resolve are “SOI-SOC2” satellite-mounted microprocessor units (MPUs) jointly developed by JAXA and MHI. They provide outstanding reliability under space-unique environments through high radiation resistance capability while ensuring high-speed data processing.
MHI, with its rich experience and accumulated technological knowledge in developing sensors and electronic instrumentation for numerous scientific satellites, continues to make valuable contributions to diverse cosmic fields.
Mitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com.
TANAKA Contributes to Global Vascular, a Medical Venture Company Developing a Stent Delivery System for Lower Limb Atherosclerosis
Strengthening commitment to the medical device field and contributing to the development of the medical device industry in Japan
TOKYO, Dec 12, 2023 – (JCN Newswire) – TANAKA Kikinzoku Kogyo K.K. (Head office: Chiyoda-ku, Tokyo; Group CEO: Koichiro Tanaka), which develops industrial precious metals products as one of the core companies of TANAKA Precious Metals, announced that it has contributed to Global Vascular Co., Ltd. (Head office: Shinjuku-ku, Tokyo; CEO: Kenta Bito; COO: Shunto Maegawa), a medical venture company developing a medical device for the treatment of lower limb ischemia that serves as a stent delivery system for lower limb atherosclerosis. This equity infusion represents a direct investment into a company by DMC (Diamond Medino Capital) 1st Fund Investment Limited Partnership – a medical venture capital fund that TANAKA formally committed to supporting in November 2022.
About Global Vascular Co., Ltd.
Global Vascular Co., Ltd. is a medical venture company established in 2022. It is headed by Kenta Bito and Shunto Maegawa, who have been engaged in biomaterials research since 2013 as part of the Hasebe Research Group led by Terumitsu Hasebe, a professor at the Tokai University School of Medicine. Global Vascular Co., Ltd. has pioneered the development of a stent delivery system specifically for the treatment of atherosclerosis in the below-knee region. It is currently attracting worldwide attention as a new treatment method in the growing market for lower limb stents, where there are high hurdles for stent development due to high recurrence rates after treatment.
Background and Aim of Investment
The “Stent Delivery System for Lower Limb Atherosclerosis,” the development business of Global Vascular Co., Ltd., is the culmination of the innovative stent design technology and high-performance surface modification technology pioneered by Mr. Hasebe, a world-class researcher in the development of endovascular treatment devices. TANAKA believes that this contribution will deepen the connection between the development framework lead by Mr. Hasebo and the medical venture ecosystem, in the advancement of endovascular treatment devices.
Representatives Mr. Bito and Mr. Maegawa are the co-developers of the basic technology, as well as the researchers and managers who are expected to become leaders in the lower limb stent market in the future.
Through this contribution, TANAKA aims to broaden its presence in the medical sector by innovating new products and technologies while accumulating knowledge in the stent industry and forming business alliances for the future.
Overview of Global Vascular Co., Ltd.
Representatives: Kenta Bito, Shunto Maegawa Founded: December 12, 2022 Capital: 282 million yen (including capital reserve) Head office: Ichigaya Science and Technology Innovation Center Building 2F, 3-8 Ichigayatamachi, Shinjuku-ku, Tokyo, 162-0843 Business Description: Design and development of medical equipment, research, consulting, etc. Investor: Diamond Medino Capital Inc.
About TANAKA Precious Metals
Since its foundation in 1885, TANAKA Precious Metals has built a portfolio of products to support a diversified range of business uses focused on precious metals. TANAKA is a leader in Japan regarding the volumes of precious metals handled. Over the course of many years, TANAKA has not only manufactured and sold precious metal products for industry but also provided precious metals in such forms as jewelry and assets. As precious metals specialists, all Group companies in Japan and around the world collaborate and cooperate on manufacturing, sales, and technology development to offer a full range of products and services. With 5,355 employees, the group’s consolidated net sales for the fiscal year ending March 31, 2023, was 680 billion yen.
Global industrial business website https://tanaka-preciousmetals.com/en/
Nearly half of ASEAN based respondents perceived legacy IT infrastructure and systems to be a challenge to digital transformation (DX) and innovation projects within their own company, according to a survey conducted by AIBP in 2021. The survey counted 206 professionals in the public services sector across the largest economies in Southeast Asia: Indonesia, Malaysia, Thailand, Philippines & Vietnam. The same survey showed that 60.6% of respondents believe that business intelligence software is the DX solution that brings the largest benefits to their organisation.
Sustainability has also been a growing focus in ASEAN, illustrated by the sustainable mobility and energy targets of ASEAN. The Phnom Penh Declaration on Sustainable Urban Mobility is the first Declaration on sustainable transport issued by the ASEAN Transport Ministers focusing on urban and metropolitan regional mobility. The ASEAN Plan of Action for Energy Cooperation demonstrates the region’s commitment to achieving the targets on renewable energy share 23% in total primary energy supply, as well as the 35% share in installed power capacity by 2025. The need for education is underlined as well from a 2021 AIBP survey, where the lack of talent and expertise was ranked as the most significant impediment to digital transformation in ASEAN. In advancing these public interests, tech-powered innovation has and will continue to be key.
Tech-powered innovation has continued to be key in advancing public interests such as mobility, sustainable energy and education.
Taiwanese Companies Contributing to ASEAN Societies
Mobility: With transport mobility being integral to driving economic and social growth, importance is placed on developing innovations in this area and several companies have stepped up to take the lead. PLANET Technology Corporation has solved key issues pervading public transport networks with their Industrial LoRaWAN Wireless Gateway solution. It facilitates data transmission over long-range distances at low power consumption across urban and rural areas, and supports real-time data collection, enabling vehicle detection and location tracking. This contributed to smart parking solutions and allowed commuters to easily check bus timings, improving the overall public transport system.
Up-and-coming alternative mobility solutions are getting increased attention as well. Advancements made in vehicle electrification have contributed to the lowering cost of electric vehicles (EV). Coupled with an increasing focus on sustainability in ASEAN, EV adoption and the development of an EV ecosystem are growing. Zealio is one of the key players in the EV interior space. Guided by a user-centric approach, Zealio sought to develop EV components that are easy to install, have zero-interference with other vehicle electronics, are energy efficient and recyclable.
Sustainable Energy: Environmental concerns are increasing in ASEAN. Stakeholders in the energy industry are seeking to pivot to a green energy approach and Advantech is at the forefront of this change. Advantech has observed that power plant and grid owners are most concerned about data accuracy, operational efficiency and asset management. To address these needs, the company has developed a smart energy management solution that includes pre-built related analytics. In helping Singapore’s National Water Agency (PUB) with the monitoring and tracking of their Floating Solar PV System, Advantech partnered with Mirai Electronics to build an IoT framework that gathers critical equipment and environmental data that is sent to the cloud, various dashboard views including green parameters to facilitate data analytics and visualisation, and a system that enables proactive monitoring and response to tough environmental conditions.
Need for Skill Development through Tech-Enabled Education: A 2021 survey conducted by AIBP showed that 39.4% of public services stakeholders believe people are the principal challenge to becoming data driven. As technology continues to play a key role in innovation efforts, workforce skill levels need to keep up and education is integral to nurturing that talent. Enterprises have recognised this need and are providing tech-enhanced solutions to complement traditional educational methods.
In pursuit of closing the gap, one successful project was delivered by CYP’s Pro AV solutions. CYP integrated their AV solutions together with learning tools such as document cameras, interactive white boards and audio visual devices providing a solution for Vietnam National University, Hanoi (VNU)’s remote learning programmes. This has enabled the concept of smart classroom, which aims to deliver high-quality classes during distance learning and video conferencing, and let teachers engage both in-class and remote students.
Another technology provider, IPEVO, has also demonstrated strong commitment to provide real-time image capture document cameras to DIGI@Education, driving student engagement in a hybrid setting. On top of education, IPEVO is able to support corporate trainings, legal and healthcare sectors.
About AIBP
AIBP serves as an avenue for public and private organisations in Southeast Asia to access and exchange information about growth and innovation within the B2B space. With a current network of over 30,000 stakeholders in Southeast Asia, AIBP continues to develop ecosystems by engaging in activities which create value-adding information for our stakeholders seeking to make transformative impacts within their organisations. For additional information about AIBP, please visit https://iotbusiness-platform.com/.
About Taiwan Excellence Awards
Advantech, Cypress, IPEVO, PLANET, and Zealio were recently recognized by the Taiwan Excellence Awards. These awards have been established by the country’s Ministry of Economic Affairs since 1993 to celebrate how technological innovation helps people live more rewarding lives. Each year, the Taiwan Excellence Awards select the most innovative products in Taiwan across four major categories: R&D, design, quality, and marketing. As well as recognizing domestic achievement, the awards serve as a benchmark for innovation and excellence in international markets. Please visit https://www.taiwanexcellence.org/en for more information.
The survey counted 206 professionals in the public services sector across the largest economies in Southeast Asia: Indonesia, Malaysia, Thailand, Philippines & Vietnam. The same survey showed that 60.6% of respondents believe that business intelligence software is the DX solution that brings the largest benefits to their organisation.
Sustainability has also been a growing focus in ASEAN, illustrated by the sustainable mobility and energy targets of ASEAN. The Phnom Penh Declaration on Sustainable Urban Mobility is the first Declaration on sustainable transport issued by the ASEAN Transport Ministers focusing on urban and metropolitan regional mobility. The ASEAN Plan of Action for Energy Cooperation demonstrates the region’s commitment to achieving the targets on renewable energy share 23% in total primary energy supply, as well as the 35% share in installed power capacity by 2025. The need for education is underlined as well from a 2021 AIBP survey, where the lack of talent and expertise was ranked as the most significant impediment to digital transformation in ASEAN. In advancing these public interests, tech-powered innovation has and will continue to be key.
Tech-powered innovation has continued to be key in advancing public interests such as mobility, sustainable energy and education.
Taiwanese Companies Contributing to ASEAN Societies
Mobility: With transport mobility being integral to driving economic and social growth, importance is placed on developing innovations in this area and several companies have stepped up to take the lead. PLANET Technology Corporation has solved key issues pervading public transport networks with their Industrial LoRaWAN Wireless Gateway solution. It facilitates data transmission over long-range distances at low power consumption across urban and rural areas, and supports real-time data collection, enabling vehicle detection and location tracking. This contributed to smart parking solutions and allowed commuters to easily check bus timings, improving the overall public transport system.
Up-and-coming alternative mobility solutions are getting increased attention as well. Advancements made in vehicle electrification have contributed to the lowering cost of electric vehicles (EV). Coupled with an increasing focus on sustainability in ASEAN, EV adoption and the development of an EV ecosystem are growing. Zealio is one of the key players in the EV interior space. Guided by a user-centric approach, Zealio sought to develop EV components that are easy to install, have zero-interference with other vehicle electronics, are energy efficient and recyclable.
Sustainable Energy: Environmental concerns are increasing in ASEAN. Stakeholders in the energy industry are seeking to pivot to a green energy approach and Advantech is at the forefront of this change. Advantech has observed that power plant and grid owners are most concerned about data accuracy, operational efficiency and asset management. To address these needs, the company has developed a smart energy management solution that includes pre-built related analytics. In helping Singapore’s National Water Agency (PUB) with the monitoring and tracking of their Floating Solar PV System, Advantech partnered with Mirai Electronics to build an IoT framework that gathers critical equipment and environmental data that is sent to the cloud, various dashboard views including green parameters to facilitate data analytics and visualisation, and a system that enables proactive monitoring and response to tough environmental conditions.
Need for Skill Development through Tech-Enabled Education: A 2021 survey conducted by AIBP showed that 39.4% of public services stakeholders believe people are the principal challenge to becoming data driven. As technology continues to play a key role in innovation efforts, workforce skill levels need to keep up and education is integral to nurturing that talent. Enterprises have recognised this need and are providing tech-enhanced solutions to complement traditional educational methods.
In pursuit of closing the gap, one successful project was delivered by CYP’s Pro AV solutions. CYP integrated their AV solutions together with learning tools such as document cameras, interactive white boards and audio visual devices providing a solution for Vietnam National University, Hanoi (VNU)’s remote learning programmes. This has enabled the concept of smart classroom, which aims to deliver high-quality classes during distance learning and video conferencing, and let teachers engage both in-class and remote students.
Another technology provider, IPEVO, has also demonstrated strong commitment to provide real-time image capture document cameras to DIGI@Education, driving student engagement in a hybrid setting. On top of education, IPEVO is able to support corporate trainings, legal and healthcare sectors.
About AIBP
AIBP serves as an avenue for public and private organisations in Southeast Asia to access and exchange information about growth and innovation within the B2B space. With a current network of over 30,000 stakeholders in Southeast Asia, AIBP continues to develop ecosystems by engaging in activities which create value-adding information for our stakeholders seeking to make transformative impacts within their organisations. For additional information about AIBP, please visit https://iotbusiness-platform.com/.
About Taiwan Excellence Awards
Advantech, Cypress, IPEVO, PLANET, and Zealio were recently recognized by the Taiwan Excellence Awards. These awards have been established by the country’s Ministry of Economic Affairs since 1993 to celebrate how technological innovation helps people live more rewarding lives. Each year, the Taiwan Excellence Awards select the most innovative products in Taiwan across four major categories: R&D, design, quality, and marketing. As well as recognizing domestic achievement, the awards serve as a benchmark for innovation and excellence in international markets. Please visit https://www.taiwanexcellence.org/en for more information.
Eisai Co., Ltd. announced today the presentation of research across various types of cancer from its oncology portfolio during the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting (#ASCO22), which is taking place virtually and in-person in Chicago from June 3 to 7. Notable presentations include a poster discussion of safety and efficacy data (NCT03386942; Abstract: #5513) from the platinum-resistant ovarian cancer cohort expansion of a Phase 1 study evaluating the antibody drug conjugate (ADC) co-developed by Eisai and Bristol Myers Squibb (Headquarters: the United States), farletuzumab ecteribulin (MORAb-202), as well as a poster presentation featuring dose optimization findings for farletuzumab ecteribulin (NCT03386942; Abstract: #3090).
“Safety and efficacy analyses in platinum-resistant ovarian cancer for farletuzumab ecteribulin suggest antibody drug conjugates may represent a promising therapeutic strategy for these patients with limited treatment options,” said Dr. Takashi Owa, President, Oncology Business Group at Eisai. “Eisai’s first antibody drug conjugate combines our in-house developed anti-folate receptor alpha antibody and our anticancer agent eribulin using an enzyme cleavable linker, illustrating our dedication to building on our medicines to improve cancer care for more patients.”
New research from the LEAP (LEnvatinib And Pembrolizumab) clinical program evaluating lenvatinib (LENVIMA) plus pembrolizumab (KEYTRUDA), the anti-PD-1 therapy from Merck & Co., Inc., Rahway, NJ, USA, includes subgroup analyses from the pivotal Phase 3 CLEAR (Study 307)/KEYNOTE-581 trial evaluating the combination in patients with advanced renal cell carcinoma (RCC) and Phase 3 Study 309/KEYNOTE-775 trial evaluating the combination in patients with advanced endometrial carcinoma (EC). A poster discussion will evaluate the impact of subsequent therapies in patients with advanced RCC receiving the combination (NCT02811861; Abstract: #4514); while a poster presentation will discuss the efficacy of next line therapy after treatment with lenvatinib plus pembrolizumab in advanced EC (NCT03517449; Abstract: #5587).
“The combination of lenvatinib plus pembrolizumab has helped to expand physicians’ arsenal of treatment options for patients living with advanced renal cell carcinoma and advanced endometrial carcinoma around the world,” said Richard C. Woodman, MD, Chief Clinical Officer, Oncology Business Group at Eisai. “Our data at ASCO 2022 demonstrate our commitment to continuing to investigate the combination through post-hoc analyses with the goal of providing healthcare professionals with tools to support them in making better-informed treatment decisions for their patients.”
In March 2018, Eisai and Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside the United States and Canada), through an affiliate, entered into a strategic collaboration for the worldwide co- development and co-commercialization of lenvatinib, both as monotherapy and in combination with pembrolizumab. To date, more than 20 trials have been initiated under the LEAP clinical program, which is evaluating the combination across more than 10 different tumor types.
In June 2021, Eisai and Bristol Myers Squibb entered into an exclusive global strategic collaboration agreement for the co-development and co-commercialization of farletuzumab ecteribulin, a folate receptor alpha (FRα)-targeting ADC. Eisai and Bristol Myers Squibb are currently investigating farletuzumab ecteribulin in FRα-positive solid tumors (inclusive of endometrial, ovarian, lung and breast cancers) in two studies: a Phase 1 clinical study in Japan and a Phase 1/2 clinical study in the United States.
This release discusses investigational compounds and investigational uses for FDA-approved products. It is not intended to convey conclusions about efficacy and safety. There is no guarantee that any investigational compounds or investigational uses of FDA-approved products will successfully complete clinical development or gain FDA approval.
For more information, visit www.eisai.com/news/2022/pdf/enews202241pdf.pdf.
Media Inquiries: Public Relations Department Eisai Co., Ltd. +81-(0)3-3817-5120
