Vesalio Announces Earl Slee as New Board Observer and Senior Advisor to the Company

 Vesalio is pleased to announce the addition of Earl Slee as a board observer and senior advisor to the company, effective immediately.

Earl brings over 35 years of medical device innovation and business development expertise to Vesalio. As an engineering and business innovator in the medical device space, Earl holds 28 U.S. patents, with innovations that have defined the standard of care in endovascular stroke treatment. The 1998 neurovascular start-up where he led R&D climbed from zero to over $1 billion in annual revenue. Most recently, he led the Technology, Strategy and Business Development group for Medtronic Brain Therapies – an organization focused on developing and commercializing endovascular therapies for hemorrhagic and ischemic stroke, as well as other neurological conditions.

Earl joined Micro Therapeutics Inc. in 1998 as VP of R&D, where he led the development of a treatment for arteriovenous malformations. In 2006, after ev3 acquired Micro Therapeutics, he served as VP of R&D and invented the first stent-retriever for acute ischemic stroke (Solitaire FR). In 2010, after Covidien acquired ev3, Earl continued to serve as VP of R&D and Business Development and was integrally involved in launching the Pipeline Flow Diverter. When Medtronic acquired Covidien in 2015, Earl served as interim VP/General Manager of the Enabling Technology business (>$1B in annual revenue), earned the 2017 Patent of Distinction award, and was inducted as a Bakken Fellow in 2016. Earl retired from Medtronic in October 2020.

“I am impressed with the drive of Vesalio to create innovation focused on improving patient care during a life-threatening vascular event,” said Earl Slee. “We need to do more to ensure all patients with a blood clot get the help they need to live life as fully as possible. I look forward to being part of Vesalio’s effort to bring to market solutions that reimagine, improve and progress the treatment of vascular conditions.”

Earl holds a bachelor’s degree in physics with a minor in mechanical engineering from the University of California, San Diego. He also holds an MBA from the Tuck School of Business, Dartmouth College and an MSEE from San Diego State University.

“We are delighted to have Earl Slee join our mission,” remarked Steve Rybka, Vesalio chief executive officer. “With his years of innovation and leadership in the neurovascular and neurosurgery markets, Earl’s guidance will be invaluable as we further develop the NeVaTM neurovascular platform and as we extend our proprietary clot removal technologies into other thrombectomy applications.”

About Vesalio

Founded in 2013, Vesalio is a privately held medical device company focused on advancing patient care in vascular occlusion by providing physicians superior technology designed to improve clinical outcomes. The Company’s proprietary NeVa™ platform was designed to consistently achieve first-pass recanalization in acute ischemic stroke by effectively removing all types of neurovascular clots from patient anatomy. For more information, visit vesalio.com.

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Vesalio Announces Appointment of Mike Kujak as Its New Independent Board Chairman

 Vesalio is pleased to announce the appointment of Mike Kujak as chairman of its Board of Directors. In this role, Mike will bring expert knowledge and know-how from his years of leadership in the medical device start-up space.

“Mike’s leadership experience in scaling multimillion-dollar medical device start-ups will be a valuable addition to our Board of Directors,” said David Adair, M.D., Vesalio board member and managing partner of venture capital firm Solas BioVentures. “With Mike, we’re even more excited by the collective expertise the board is bringing to Vesalio as we transform the way strokes are treated and position the company for long-term growth and profitability.”

Mike brings over 35 years of broad and strategic healthcare leadership experience in medical devices, pharmaceuticals, biotechnology, clinical research and payer economics. He currently serves as the president and chief executive officer of Francis Medical, a start-up medical device company, developing water vapor technology for treating prostate cancer. Before Francis Medical, Mike was the chief marketing officer and senior vice president of International for NxThera, a start-up medical device company purchased by Boston Scientific. Prior to NxThera, he served as vice president and general manager of the Prostate Health business unit of American Medical Systems, which developed and commercialized medical device solutions to treat benign prostatic hyperplasia (BPH), prostate cancer and stone disease. Mike received his MBA from the OPUS College of Business, University of St. Thomas in St. Paul, Minnesota, and a Bachelor of Science in physics and chemistry from the University of South Dakota.

“Vesalio’s revolutionary blood clot removal technology and focus on expanding its market globally make it an exciting time to join the company,” said Mike Kujak. “I look forward to bringing my years of experience in medical device start-ups, enterprise sales, and international commercialization to the board.”

“As a proven leader, Mike will have an immediate impact on our strategic execution,” remarked Steve Rybka, Vesalio chief executive officer. “His guidance and oversight will further enhance our ability to deliver life-saving innovation to physicians and their patients.”

About Vesalio

Founded in 2013, Vesalio is a privately held medical device company committed to advancing patient care in vascular occlusion by providing physicians superior technology designed to improve clinical outcomes. The company’s proprietary NeVa™ platform was designed to consistently achieve first-pass recanalization in acute ischemic stroke by effectively removing all types of neurovascular clots from patient anatomy. For more information, visit vesalio.com.

About Solas BioVentures

Solas BioVentures is a venture capital firm that invests exclusively in the life science industry, focusing on early and development stage Biotech and MedTech companies advancing impactful, disruptive technologies. Headquartered in Chattanooga, Tennessee, its coverage is global. For more information, visit solasbio.com.

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William von Brendel

858-335-5790

www.vesalio.com

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Vesalio Initiates Clinical Study Evaluating Innovative Thrombectomy Technique for Patients with STEMI

 Today, Vesalio announced the start of enrollment in its NATURE study using enVast™, the company’s first thrombectomy system for patients presenting with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention.

NATURE is a randomized, multi-center clinical trial comparing the safety and efficacy of enVast™ as an adjunctive measure to conventional intervention versus the standard of care in STEMI patients with large thrombus burden.

The first patient in the study was enrolled by Professor Marco Valgimigli, Deputy Chief of Cardiology at Cardiocentro Ticino Istituto, in Lugano, Switzerland.

“Our first-in-human case series of 61 STEMI patients with large thrombus burden allowed us to develop a safe and effective thrombectomy technique using the enVast™ stent retriever under continuous aspiration. With the NATURE study, our goal is to assess the comparative effectiveness of this novel technique versus the standard of care. The results could provide a new therapeutic opportunity for patients with large thrombus burden, who still represent a major challenge for procedural success and long-term outcomes,” said Dr. Valgimigli.

Coronary Artery Disease is the number one cause of death globally. Approximately 17 million patients experience myocardial infarction every year, with more than 3 million presenting with a large thrombus burden in STEMI.

“We are excited to diversify the use of our Drop Zone™ technology and venture into this critical indication, where we anticipate making a positive impact on patient outcomes as Vesalio has achieved in stroke intervention,” commented Steve Rybka, Vesalio Chief Executive Officer.

The Vesalio enVast™ coronary thrombectomy system is CE approved.

About Vesalio

Founded in 2013, Vesalio is a privately held medical device company committed to advancing patient care in vascular occlusion by providing physicians superior technology designed to improve clinical outcomes. The company’s proprietary NeVa™ platform was designed to consistently achieve first-pass recanalization in acute ischemic stroke by effectively removing all types of neurovascular clots from patient anatomy.

For more information, please visit vesalio.com, email info@vesalio.com, or connect with us on LinkedIn or Twitter.

Vesalio

William von Brendel

858-335-5790

www.vesalio.com

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Vesalio Attains Key FDA Clinical Study Milestone

Vesalio announces it has accomplished a key FDA IDE study milestone to support entry into the US neurovascular market. Enrollment in the VITAL(1) clinical trial, assessing the company’s NeVa VS™ technology in the treatment of symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage (aSAH), has been completed.

Cerebral vasospasm is an intense and prolonged narrowing of the arteries that develops gradually over the first few days following aneurysm rupture. This narrowing can reduce blood flow and is considered to be one of the leading causes of death after such ruptures. Current treatment for vasospasm includes endovascular administration of intra-arterial vasodilators and balloon angioplasty, utilized off-label for this indication. Currently, there is no medical technology cleared for the treatment of vasospasm in the United States.

“Completion of this IDE study is a significant step forward in our drive to provide the first FDA cleared technology to treat this patient population. We look forward to working with the FDA in the next step of the regulatory process,” stated Steve Rybka, CEO of Vesalio.

(1) VITAL refers to “The Vesalio NeVa VS for the treatment of symptomatic Cerebral Vasospasm following aneurysmal subarachnoid haemorrhage (aSAH).”

Founded in 2013, Vesalio is a privately held medical device company focused on advancing patient care in vascular occlusion by providing physicians superior technology designed to improve clinical outcomes. The Company’s proprietary NeVa™ platform was designed to consistently achieve first-pass recanalization in acute ischemic stroke by effectively removing all types of neurovascular clots from patient anatomy.

For further information, visit www.vesalio.com or email info@vesalio.com. NeVa trademark and patents are the property of Vesalio.