Biochemical reagents are chemicals found in biological systems that can be used in life science research. They could be organic compounds or biological substances. Various reagents such as buffers, detergents, antimicrobials, enzyme inhibitors and substrates are currently available for biochemical, molecular and cell biology research. Every technique or workflow throughout research, ranging from molecular biology, cellular analysis, to protein detection, requires the participation of biochemicals with specific properties. Critical reagents directly affect the quality, consistency, and specificity of results. When selecting the key biochemical reagents, one should fully understand the lot-to-lot consistency, performance, and biochemical or biophysical properties of the reagents.

Detergents are amphiphilic compounds consisting of both hydrophilic and hydrophobic domains. They spontaneously form spherical micellar structures in aqueous solutions to provide an amphiphilic environment that mimics lipid bilayers. Due to the high water solubility of detergent molecules, they play a crucial role in the extraction, purification and stabilization of membrane proteins. Thus detergents are frequently used in molecular biology research such as cell lysis, protein purification, DNA/RNA separation, electrophoresis, immunoassays, and cleaning.

Amerigo Scientific provides high-quality biochemical reagents for various life science research, including detergents, catalysts, enzymes and substrates, inhibitors and more. These reagents can be effectively browsed in the extensive catalog according to the specific research application. Nevertheless, Amerigo Scientific has recently expanded its portfolio of detergents and launched CALX8 Reagent (Soft proprietary detergent) for the laboratory researchers to extract membrane proteins of the highest quality.

The CALX8 reagent is an ionic calixarene-based detergent/surfactant with three polar carboxylic groups and a octyl chain. Detergents are classified into three major categories according to their structure. Ionic detergent, as one of the three categories, contains a head group with a net cationic or anionic charge. Ionic detergents are very effective at solubilizing proteins, as well as denaturing proteins.

If you need more information about the CALX8 Reagent or have any inquiries about Amerigo Scientific’s biochemical reagents products, please visit

About Amerigo Scientific

Amerigo Scientific is a distribution company that focuses on providing critical products and services to the biomedical and life science research communities. Albeit this is a new company, Amerigo Scientific’s founder possesses more than 20 years of experience in the biomedical as well as biochemical fields and has established close contacts with key personnel in top international pharmaceutical, biotech companies, academic research institutes, and government research agencies. It has a professional team, equipped with excellent technical support and thoughtful customer service. As most of its employees have earned a graduate (Ph.D. or M.S.) degree in life science, they can comprehend customers’ questions or concerns and are always ready to provide individualized customer service of high standards.