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“Chromatography Reagents market is driven by growing academic and industrial research and development (R&D) spending on pharmaceutical products, technical developments in chromatographic reagents and the growing importance of chromatographic testing in drug approvals.”

Chromatography Reagents Market size is forecast to reach $17.46 billion by 2025, after growing at a CAGR of 7.2% during 2020-2025. The Chromatography Reagents market is driven by growing academic and industrial research and development (R&D) spending on pharmaceutical products, technical developments in chromatographic reagents and the growing importance of chromatographic testing in drug approvals.

Reagents – Segment Analysis
Liquid Chromatography held the largest share in the Chromatography Reagents market in 2019. Liquid chromatography (LC) is a chromatographic analytical technique that is useful for separating the ions or molecules dissolved in a solvent. Such distinction occurs depending on the sample’s interactions with the mobile and stationary phases. Separation from liquid chromatography is based on the analyte’s preference for both the stationary and mobile phases. Silica is one of the most common liquid-chromatography adsorbent materials. The key prerequisite for the mobile process is that the components are dissolved up to the concentration appropriate for the detection. The type of mobile step may have a significant impact on the separation retention time as well as the downstream detection ionization of the components. Mobile phase pH can play an important role in the retention of a part and can affect selectivity.

Bed Shape – Segment Analysis
Column bed shape held the largest share in the Chromatography Reagents market in 2019. Column bed shape chromatography is a separation technique in which the stationary bed is within a tube. The solid stationary phase particles or the support coated with a liquid stationary phase can fill the entire inside volume of the packed column tube or be concentrated on or along the inside tube wall, leaving an open, unregulated path in the middle part of the tube for the mobile phase. Silica gel are widely used for column chromatography. In gel sedimentation, spherical silica gel is superior to irregularly shaped silica gel, and forms more uniform column beds. They have started to be used extensively to industrial-scale preparatory research for laboratory-scale purification.

Separation Mechanism – Segment Analysis
Adsorption held the largest share in chromatography reagents market in 2019. Chromatographic adsorption has many uses. In general, it is used to determine a compound’s concentration (or purity), to divide a mixture into individual components and to classify what is in a mixture. There are three main types of chromatographic adsorption, column, thin layer, and gas-solid. Thin layer chromatography is widely used chromatographic adsorption technique where the mobile phase is liquid. Adsorption can be further defined based on the strength of the interaction between the adsorbent molecules and the adsorbents.

Application – Segment Analysis
Food and beverages has been the primary market for Chromatography Reagents in 2019 growing at a CAGR of 9.2%. Chromatographic reagents are commonly used for effective purification of crystalline sugar and liquid sugar syrup in the food and beverage industry. These reagents remove salt ions from the rough solutions and adsorb the yellowish-brown substances which give natural color to raw sugar. In the past decade, the global food and beverage (F&B) industry has seen a steady growth and this is expected to continue. The food sector plays an essential role in the US economy, accounting for about 5 percent of gross domestic product. The food industry has $1.4 trillion in gross sales from food eaten at home and away from home. Asia Pacific, where average spend is expected to increase by 7.5% per year on food and beverages. The Middle East & Africa region is forecast to see average annual growth of 7.3%. The growth in the food and beverages sector will augment chromatography reagents market.

Geography – Segment Analysis
North America dominated the Chromatography Reagents market with a share of more than 38%, followed by Europe and APAC. The increased use of chromatography technique, primarily in the food and beverage and pharmaceutical industries, drives the region’s demand for chromatographic reagents. With the rise of the region’s aging population and the increasing number of essential diseases, healthcare spending in the area has increased significantly. This increased R&D investments for drug discovery and production in the pharmaceutical industry which further increased demand for chromatography technique and reagents in the area. The United States stood as the biggest user of reagents to chromatography. In the United States, healthcare is the largest portion of federal expenditures. Currently, the outbreak of COVID-19 pandemic has increased the research activity to discover the COVI-19 vaccine. The COVID-19 pandemic is of grave concern to the biopharmaceutical research and development industry. Outbreaks of novel infections with viruses for which no known successful antiviral therapy exists pose a significant challenge to public health. This has increased the research activity which has augmented the usage of chromatography process into drug and research sectors. The rise in utilization rate of chromatography have strengthened the reagents use. But the COVID-19 has affected other industries economically due to temporarily lockdown as well as no production activity across the North America region and at global level.

Drivers – Chromatography Reagents Market

Wide application of Chromatography Reagents
Chromatographic reagents reflect the increasing need for technology and the rising number of pharmaceutical and biotech companies. In addition, the growth in the use of this technique in genomics, proteomics, innovation and metabolomics medicine is also expected to fuel the demand in the forecast period. In addition, the need for chromatographic reagents to meet the requirements of the food and beverage, semiconductor, chemical and environmental testing industries is also expected to boost the demand.

Challenges – Chromatography Reagents Market

High Price of Chromatography Reagents can hamper the market
The enormous price of technology, which includes automated features and device design, is expected to hinder the growth of the chromatography reagent industry. The other factor responsible for high price is the high quality of reagents.

Market Landscape
Technology launches, acquisitions and R&D activities are key strategies adopted by players in the Chromatography Reagents market. In 2019, the market of chromatography reagent has been consolidated by the top five players accounting for xx% of the share. Major players in the Chromatography Reagents Market are Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Dani Instruments S.P.A, Sigma-Aldrich Corporation, and Thermo Fisher Scientific among others.

Acquisitions/Technology Launches
In September 2015, StoneCalibre, LLC one of its affiliates, Edge BioSystems, Inc., has acquired the Ion Chromatography Business from Transgenomic, Inc. The acquisition will boost Edge BioSystems Inc., portfolio for researching, developing, manufacturing, and marketing high quality bulk resins and high performance liquid chromatography (“HPLC”) columns with applications across diverse fields such as pharmaceuticals, foods, life sciences, environmental, and forensics.

Key Takeaways
North America dominates the Chromatography Reagents market owing to the wide study on biologic and drugs in this region.
Chromatographic reagents are commonly used for efficient purification of crystalline sugar and liquid sugar syrup in the food and beverage industry.
Aluminum oxide is well-known adsorbent stationary process, which is used in chromatography for less polar compounds. Aluminum oxide powder is a highly porous aluminum white to off white, fine and grained powder.
The characteristics of aluminum oxide chromatography are determined by the particular (internal) surface area measured by the BET process, it means the diameter of the pore and the volume of the pore.
The growing popularity of green chromatography and the increasing use of chromatography techniques in proteomics, genomics and metabolomics medicines are expected to produce new prospects for further expansion of the demand for chromatographic reagents.

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